Bach's F major is a robust and powerful key, and this prelude also conveys a sense of grandeur. While it is presumed to have been written for harpsichord, it would not sound out of place on the organ. Numerous ornaments are scattered throughout, and it is certainly correct to consider these ornaments as being played freely and improvisationally, rather than strictly in time.

It is fundamentally written in three voices, with the latter half of the theme used in sequences, and many strettos are also observed. In that sense, this prelude is written in a fugal manner, adhering to the order of polyphony, so performers should certainly aim for the independence of each voice.

The highest note in this prelude is G in measure 20, where the theme appears, and this section is a continuous series of harmonic sequences. Measure 20 can be considered a peak point.

The final chord is in five voices. It should ideally conclude with a slow crescendo towards this chord.